Pentosan

Pentosan (Elmiron) is a drug used for treating bladder pain caused by interstitial cystitis. The drug, which is a weak blood thinner, is believed to relieve bladder discomfort by helping to rebuild the mucous lining of the bladder. Pentosan comes in the form of a capsule that is taken three times a day. Potential side effects of this drug may include hair loss, headache, and bruising. If you are taking this drug, keep in mind that it may take up to six months to see improvement in your symptoms.

What Is Pentosan?

Pentosan polysulfate sodium is a prescription medicine sold under the brand name Elmiron^®.

What Is Pentosan Used For?

Pentosan is used to help relieve bladder pain or discomfort associated with interstitial cystitis (IC). Pentosan is the first and only oral medication to be approved by the FDA for this indication.

Pentosan has not been approved for use in children.

Pentosan: How Does It Work?

Pentosan is actually a weak blood thinner. It is not completely understood how pentosan works, but it is believed that it works by helping to rebuild the mucous lining of your bladder.

After taking pentosan, the drug dissolves and eventually ends up in your bladder. Here, it sticks to the bladder wall (instead of being removed with urine) and helps rebuild the lining.

Pentosan: Effects

In clinical studies, pentosan was able to improve bladder pain in about 38 percent of women with chronic interstitial cystitis, while 18 percent of women taking a placebo (sugar pill) had improved symptoms of interstitial cystitis. Patients may not feel relief from interstitial cystitis pain for the first two to four months. A decrease in urinary frequency may take up to six months. Patients are urged to continue with pentosan for at least six months to give the drug an adequate chance to relieve interstitial cystitis symptoms.

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