Interstitial cystitis is a chronic condition that can cause discomfort or pain in the bladder and the surrounding pelvic region. People with interstitial cystitis have an inflamed or irritated bladder wall. This inflammation may lead to scarring and stiffening of the bladder, less bladder capacity, and pinpoint bleeding in the bladder lining. Symptoms of interstitial cystitis include discomfort, pressure, tenderness, or intense pain in the bladder and surrounding pelvic area; an urgent and frequent need to urinate -- both day and night; and reduced bladder capacity.