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More Medicines That Interfere With Cipro XR

QT-Prolonging Medications
In general, Cipro XR should be used with caution with any other medications that can cause QT prolongation (a certain change in the heart rhythm). Taking Cipro XR with these medications may increase the risk of a life-threatening arrhythmia. Talk to your healthcare provider about this interaction if you take any QT-prolonging drugs.
 
Methotrexate
Cipro XR may increase the amount of methotrexate in your blood, increasing your risk for potentially serious side effects. If you take these medications together, your healthcare provider may need to monitor you closely for methotrexate toxicity.
 
Mycophenolate
Cipro XR may reduce the amount of mycophenolate in your blood, potentially decreasing its effectiveness. If you take these medications together, your healthcare provider may need to monitor you more closely to make sure mycophenolate is working for you.
 
NSAIDs
There have been reports of seizures in clinical trials when NSAIDs where given in combination with high doses of medications like Cipro XR. Check with your healthcare provider before taking these drugs together.
 
P-Glycoprotein Inducers
P-glycoprotein (Pgp) is a protein found in the body. One of its roles is to help remove substances from the body, such as medications. Cipro XR is one of the drugs partly removed from the body by Pgp. Medications known as Pgp inducers increase the action of Pgp. Thus, taking Cipro XR with a Pgp inducer may decrease the amount of Cipro XR in your blood, potentially making it less effective.
 
Your healthcare provider may need to monitor you more closely if you take these drugs together to make sure your infection is completely resolved.
 
P-Glycoprotein Inhibitors
P-glycoprotein (Pgp) is a protein found in the body. One of its roles is to help remove substances from the body, such as medications. Cipro XR is one of the drugs partly removed from the body by Pgp. Medications known as Pgp inhibitors decrease the action of Pgp. Thus, taking Cipro XR with a Pgp inducer may increase the amount of Cipro XR in your blood, potentially increasing your risk for side effects.
 
Your healthcare provider may need to monitor you more closely if you take such drugs together.

Cipro XR Antibiotic Information

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