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Important Info on Tendon Problems With Cipro XR

Who Is at Risk?

Tendon rupture can occur in anyone who takes Cipro XR. However, some people appear to have a higher risk than others. This includes people who:
 
  • Are over 60 years of age
  • Take corticosteroid medications (see Cipro XR Drug Interactions)
  • Have had kidney, heart, or lung transplants
  • Engage in strenuous physical activity
  • Have kidney failure (renal failure)
  • Have a history of tendon problems, such as rheumatoid arthritis.
     
However, tendon problems have also been reported in people who did not seem to have any of these risks.
 

Signs of Tendon Problems With Cipro XR

If you are taking Cipro XR or other quinolones, watch for any signs of tendonitis or tendon rupture, including:
 
  • Tendon pain, swelling, or inflammation
  • A snapping or popping sound, followed by sharp pain in a tendon area
  • Immediate bruising after an injury to a tendon area
  • Weakness
  • Difficulty moving joints or walking.
     
Most tendon problems with fluoroquinolones, including Cipro XR, occur about eight days after starting treatment. However, problems can happen as early as within two hours after the first dose, or as late as six months after treatment has stopped.
 

Talking to Your Healthcare Provider

Talk to your healthcare provider about possible tendon problems before you begin treatment with Cipro XR, especially if you have any of the risks listed earlier. If you develop signs of tendon problems, or if you experience a ruptured tendon while taking Cipro XR, stop taking the medication and contact your healthcare provider right away. Do not exercise or use the affected area until your healthcare provider makes sure you do not have a ruptured tendon.
 

Cipro XR Antibiotic Information

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